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1994-10-25
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Document 2250
DOCN M94A2250
TI HIV and HCV prevalence in childbearing women at outcome of pregnancy in
the Paris area, France.
DT 9412
AU Couturier E; Six C; Brossard Y; Larsen M; Henrion R; Brunet JB; European
Centre for the Epidemiological Monitoring of AIDS,; Saint-Maurice,
France.
SO Int Conf AIDS. 1994 Aug 7-12;10(1):347 (abstract no. PC0618). Unique
Identifier : AIDSLINE ICA10/94370325
AB OBJECTIVE: To determine the prevalence of HIV and HCV infection in
childbearing women at outcome of pregnancy (deliveries, abortions,
ectopic pregnancies) in all medical settings in the Paris area. METHODS:
Blood samples were collected on filter papers for all women in all
medical settings (public and private) during a 4-week period in 1993.
For each woman, variables included pregnancy outcome, age, residence
area code and country of birth. Unlinked HIV antibody testing was
carried out on all filter papers. Unlinked HCV testing (ORTHO HCV 3.0
and CHIRON RIBA 3.0) was carried out on a stratified sample: 1 out of 2
for women born in France and all papers in foreign born women. RESULTS:
Out of 10,617 papers collected, 7,072 had both tests performed. HIV
prevalence was 0.6% [95% CI 0.4-0.7] and weighted HCV prevalence
estimate was 1.3% [95% CI 1.0-1.6]. HCV and HIV prevalences by pregnancy
outcome are shown in the table for women with a known outcome. TABULAR
DATA, SEE ABSTRACT VOLUME. HCV estimates were not different by
country/region of birth (France: 1.4%; N. Africa: 1.5%; Subsaharan
Africa/the Caribbean: 1.6%; other countries: 0.8%). In contrast, HIV
prevalences differ by country/region (respectively, 0.4%, 0.4%, 1.7%,
0%). HIV prevalence was 13% for HCV (+) women compared to 0.4% for HCV
(-) women. CONCLUSION: This unlinked exhaustive survey of childbearing
women allows estimates of HCV and HIV prevalence. HCV estimates are high
in this heterosexual population. For women undergoing abortion, results
are consistent with a possible common risk factor (IV drug use) for HCV
and HIV transmission.
DE Abortion, Legal Adult Female Hepatitis C/*EPIDEMIOLOGY/TRANSMISSION
Human HIV Infections/*EPIDEMIOLOGY/TRANSMISSION HIV Seroprevalence
Infant, Newborn Paris/EPIDEMIOLOGY Pregnancy Pregnancy Complications,
Infectious/*EPIDEMIOLOGY/ETIOLOGY Pregnancy Outcome Risk Factors
Urban Population/*STATISTICS & NUMER DATA MEETING ABSTRACT
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).